Welcome!
Welcome to the Zhu lab at Georgia Tech. We study single molecular adhesion with force spectroscopy for various cells and disease models. We pioneered in the discovery of force-prolonged bond lifetime, or the “catch bond,” using the biomembrane force probe paired with mutation studies and molecular dynamics simulations.
Highlights
Our Research
Our goal is to understand how mechanical force influences enzyme-linked receptors, such as T cell receptors (TCRs) and B cell receptors (BCRs), to drive effective signal transduction.
Our Projects
By using tools like biomolecular force probes and molecular tension probes, we study the mechanobiology of single-molecule ligand–receptor interactions and their downstream effects.
Our Team
Meet the people behind the research. Our team brings together scientists at all levels who share a passion for exploring the mechanics of immune signaling and advancing biomedical discovery.